Description

Spiro[Bicyclo[2.2.1]Heptane-2,2-Oxirane], 7,7-Dimethyl-, (1R,2R,4R)- (9Ci) is a high-purity, stereochemically defined spirocyclic epoxide building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional structure and reactive oxirane moiety make it a valuable chiral precursor for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its unique spirocyclic framework can impart favorable biological activity and environmental stability.
• Advanced Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers, resins, and coatings with tailored thermal and mechanical properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a test substrate in the development and screening of new asymmetric catalytic systems.
• Fine Chemical Synthesis: Utilized in academic and industrial R&D for the construction of complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	Spiro[Bicyclo[2.2.1]Heptane-2,2-Oxirane], 7,7-Dimethyl-, (1R,2R,4R)- (9Ci)
CAS No.	482288-54-0
Molecular Formula	C9H14O
Molecular Weight	138.21 g/mol
Synonyms	(1R,2R,4R)-7,7-Dimethylspiro[bicyclo[2.2.1]heptane-2,2'-oxirane]; (1R,2R,4R)-7,7-Dimethyl-2-oxaspiro[bicyclo[2.2.1]heptane-2,2'-oxirane]; 7,7-Dimethylspiro[bicyclo[2.2.1]heptane-2,2'-oxirane], (1R,2R,4R)-; Spiro[norbornane-2,2'-oxirane], 7,7-dimethyl-, (1R,2R,4R)-; (1R,4R,7R)-7,7-Dimethyl-2-oxaspiro[bicyclo[2.2.1]heptane-2,2'-oxirane]; Chiral Spirocyclic Epoxide; 482288-54-0
EINECS	Contact for details

Quality Control

Our Spiro[Bicyclo[2.2.1]Heptane-2,2-Oxirane], 7,7-Dimethyl-, (1R,2R,4R)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.