Description

3-Chloro-4-Isopropoxyphenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through cross-coupling reactions, offering researchers and manufacturers a reliable path to novel compounds. This intermediate is essential for professionals in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and scalable synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, enabling the creation of new, more effective crop protection agents.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized to create boronic acid-based probes and sensors for detecting biological analytes like sugars or for protein labeling.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Chloro-4-Isopropoxyphenylboronic Acid
CAS No.	480438-56-0
Molecular Formula	C9H12BClO3
Molecular Weight	214.45 g/mol
Synonyms	(3-Chloro-4-isopropoxyphenyl)boronic Acid; 3-Chloro-4-isopropoxybenzeneboronic Acid; 3-Chloro-4-(1-methylethoxy)benzeneboronic Acid; 3-Chloro-4-(propan-2-yloxy)phenylboronic Acid; Boronic acid, B-(3-chloro-4-isopropoxyphenyl)-; 480438-56-0; 3-Chloro-4-isopropoxybenzeneboronic acid pinacol ester (related ester)
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-Isopropoxyphenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.