Description

4-Butoxy-3-Chlorophenylboronic Acid CAS NO 480438-55-9 is a specialized organoboron compound featuring a chlorinated phenyl ring with a butoxy substituent. This structure makes it a valuable boronic acid building block for Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern synthetic chemistry. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for constructing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed coupling.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating advanced organic electronic materials with tailored properties.
• Polymer Chemistry: Employed in the synthesis of functionalized polymers and dendrimers.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic synthesis and methodology development.
• Ligand & Catalyst Preparation: Used to synthesize sophisticated bidentate or polydentate ligands for catalysis.

Basic Information

Product Name	4-Butoxy-3-Chlorophenylboronic Acid
CAS No.	480438-55-9
Molecular Formula	C₁₀H₁₄BClO₃
Molecular Weight	228.48 g/mol
Synonyms	(4-Butoxy-3-chlorophenyl)boronic acid; 3-Chloro-4-butoxybenzeneboronic acid; 4-Butoxy-3-chlorobenzeneboronic acid; B-(4-Butoxy-3-chlorophenyl)boronic acid; 480438-55-9; (3-Chloro-4-butoxyphenyl)boronic acid; 4-n-Butoxy-3-chlorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-Butoxy-3-Chlorophenylboronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.