Description

n-[2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Formamide is a specialized organoboron compound featuring a formamide group, serving as a valuable synthetic intermediate. Its core value lies in its role as a protected boronic acid derivative, enabling precise cross-coupling reactions critical for constructing complex molecular architectures. This high-purity building block is essential for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced materials science, where reliable quality and structural integrity are paramount.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-boron motifs.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and inhibitors.
• Academic & R&D Laboratories: Serves as a fundamental reagent for methodological development in synthetic organic chemistry.
• Liquid Crystal & Polymer Chemistry: A building block for monomers and ligands used in functional polymer and advanced material synthesis.

Basic Information

Product Name	n-[2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Formamide
CAS No.	480425-36-3
Molecular Formula	C13H18BNO3
Molecular Weight	247.10 g/mol
Synonyms	2-Formamidophenylboronic acid pinacol ester; N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)formamide; 2-Formamidobenzene-1-boronic acid pinacol ester; (2-Formamidophenyl)boronic acid pinacol ester; B-(2-Formamidophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 480425-36-3; N-[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]formamide
EINECS	Contact for details

Quality Control

Our n-[2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Formamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.