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3-Methoxycarbonylphenylboronic Acid Pinacol Ester CAS NO 480425-35-2
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CAS No.:480425-35-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Methoxycarbonylphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial protected intermediate in modern organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, enabling the construction of complex biaryl and heterobiaryl structures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and fine chemical production.
Application
- Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
- Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific biphenyl motifs.
- Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts.
- Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors.
- Chemical Biology Probes: Useful for constructing molecular probes and tags for biochemical research and diagnostics.
- Custom Synthesis & Scale-up: A reliable starting material for contract research organizations (CROs) and CDMOs for custom synthesis projects from milligram to kilogram scale.
Basic Information
| Product Name | 3-Methoxycarbonylphenylboronic Acid Pinacol Ester |
| CAS No. | 480425-35-2 |
| Molecular Formula | C14H19BO4 |
| Molecular Weight | 262.11 g/mol |
| Synonyms | (3-(Methoxycarbonyl)phenyl)boronic acid pinacol ester; 3-(Methoxycarbonyl)benzeneboronic acid pinacol ester; Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; Benzoic acid, 3-borono-, methyl ester, 1,3-propanediol cyclic ester; Methyl 3-(pinacolboryl)benzoate; 3-Carbomethoxyphenylboronic acid pinacol ester |
| EINECS | Contact for details |
Quality Control
Every batch of 3-Methoxycarbonylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) specifying purity (typically ≥95% by HPLC/NMR), identity, and impurity profile is supplied with each shipment to guarantee batch-to-batch consistency and reliable performance in your synthetic applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder or solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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