Description

n-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Formamide is a high-purity, protected boronic acid derivative that serves as a critical synthetic intermediate. This compound matters for its role in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental to modern pharmaceutical and advanced material synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling.
• Agrochemical Research: Used in creating novel fungicides, herbicides, and insecticides with targeted activity.
• Material Science: Precursor for organic electronic materials, including polymers for OLEDs and organic photovoltaics.
• Chemical Biology: Employed in the development of bioconjugates and probes for biochemical studies.
• Library Synthesis: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.
• Academic Research: A valuable reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	n-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Formamide
CAS No.	480424-94-0
Molecular Formula	C13H18BNO3
Molecular Weight	247.10 g/mol
Synonyms	4-Formamidophenylboronic acid pinacol ester; 4-(Formylamino)phenylboronic acid pinacol ester; N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]formamide; 4-(N-Formylamino)benzeneboronic acid pinacol ester; B-[4-(Formylamino)phenyl]boronic acid pinacol ester; 480424-94-0; N-Formyl-4-aminophenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our n-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Formamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full analytical data are provided to guarantee consistency and traceability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.