Description

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Acetanilide is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, active ingredient synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the development of chemical probes and bioconjugation reagents due to its selective reactivity.
• Academic & Industrial R&D: A versatile reagent for methodology development and library synthesis in medicinal and process chemistry laboratories.
• Ligand & Catalyst Development: Used to synthesize novel ligands and complex molecules for catalytic applications.

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Acetanilide
CAS No.	480424-93-9
Molecular Formula	C16H24BNO3
Molecular Weight	289.18 g/mol
Synonyms	N-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide; 3-Acetamidophenylboronic Acid Pinacol Ester; 3-Acetylaminophenylboronic Acid Pinacol Ester; 3'-Acetamidophenylboronic Acid Pinacol Ester; (3-Acetamidophenyl)boronic Acid Pinacol Ester; B-[3-(Acetylamino)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 480424-93-9
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Acetanilide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.