Description

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl Acetate is a high-purity organoboron reagent, specifically a protected boronic ester derivative, essential for modern synthetic chemistry. Its primary value lies in serving as a key synthetic intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or phenylacetic acid motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific biaryl architectures.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, where precise molecular conjugation is critical.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the global life sciences industry.

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl Acetate
CAS No.	480424-69-9
Molecular Formula	C16H23BO4
Molecular Weight	290.16 g/mol
Synonyms	[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl] acetate; 3-Acetoxyphenylboronic acid pinacol ester; (3-Acetoxyphenyl)boronic acid pinacol ester; 3-(Pinacolatoboryl)phenyl acetate; m-Acetoxyphenylboronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-2-dioxa-1,3,2-dioxaborolan-2-yl)phenyl acetate; B-[3-(Acetyloxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5% w/w
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.