Description

3-(1,3-Dioxolan-2-Yl)Phenylboronic Acid is a specialized boronic acid derivative featuring a protected aldehyde group, making it a valuable building block in modern synthetic chemistry. Its core value lies in its dual functionality, enabling precise cross-coupling reactions while offering orthogonal reactivity for subsequent transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules and advanced intermediates.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, especially those requiring complex, functionalized aromatic systems.
• Agrochemical Synthesis: Employed in creating advanced intermediates for herbicides, fungicides, and insecticides that benefit from its specific aromatic substitution pattern.
• Material Science Research: Serves as a monomer or building block for synthesizing organic electronic materials, such as those used in OLEDs or conductive polymers.
• Ligand and Catalyst Development: Useful for preparing novel bidentate or tridentate ligands for transition metal catalysis.
• Chemical Biology Probes: Can be utilized to create boronic acid-based sensors or probes for detecting biological analytes like sugars or peroxides.

Basic Information

Product Name	3-(1,3-Dioxolan-2-Yl)Phenylboronic Acid
CAS No.	480424-60-0
Molecular Formula	C11H13BO4
Molecular Weight	220.03 g/mol
Synonyms	[3-(1,3-Dioxolan-2-yl)phenyl]boronic acid; (3-(1,3-Dioxolan-2-yl)phenyl)boronic acid; 3-(1,3-Dioxolan-2-yl)benzeneboronic acid; 2-[3-(Dihydroxyboryl)phenyl]-1,3-dioxolane; 3-(2-Dioxolanyl)phenylboronic Acid; Boronic acid, B-[3-(1,3-dioxolan-2-yl)phenyl]-; 480424-60-0
EINECS	Contact for details

Quality Control

Our 3-(1,3-Dioxolan-2-Yl)Phenylboronic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥95.0% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.