Description

Methyl 4-(3-(4-(Trifluoromethyl)Phenyl)-1,2,4-Oxadiazol-5-Yl)Benzoate is a high-value, synthetically versatile organic intermediate featuring a trifluoromethyl-substituted 1,2,4-oxadiazole core. This compound is prized for its role in facilitating the development of novel molecules with enhanced biological activity and physicochemical properties. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for lead optimization and the synthesis of advanced active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for targets requiring the modulation of lipophilicity and metabolic stability via the trifluoromethyl group.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the 1,2,4-oxadiazole moiety can contribute to biological efficacy.
• Material Science Precursor: Serves as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical manufacturers for the production of specialized, high-value compounds for client projects.

Basic Information

Product Name	Methyl 4-(3-(4-(Trifluoromethyl)Phenyl)-1,2,4-Oxadiazol-5-Yl)Benzoate
CAS No.	480390-86-1
Molecular Formula	C₁₇H₁₁F₃N₂O₃
Molecular Weight	348.28 g/mol
Synonyms	Methyl 4-[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]benzoate; Benzoic acid, 4-[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-, methyl ester; 4-(3-(4-(Trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)benzoic acid methyl ester; Methyl 4-(3-(p-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(3-(4-(Trifluoromethyl)Phenyl)-1,2,4-Oxadiazol-5-Yl)Benzoate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.