Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxaldehyde, 1-[(4-Methylphenyl)Sulfonyl]- is a high-purity, advanced pharmaceutical intermediate characterized by its sulfonyl-protected pyrrolopyridine core. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for developing new therapeutic agents.

Application

This specialized intermediate serves key roles in sophisticated organic synthesis, including:

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to develop new chemical entities.
• Bioconjugation & Probe Development: The aldehyde functional group allows for selective conjugation, useful in creating chemical probes for biological target identification.
• Agrochemical Synthesis: Serves as a building block for developing novel active ingredients with potential pesticidal or herbicidal properties.
• Material Science Precursor: Can be utilized in the synthesis of organic ligands for catalysts or functional materials.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxaldehyde, 1-[(4-Methylphenyl)Sulfonyl]-
CAS No.	479553-03-2
Molecular Formula	C15H12N2O3S
Molecular Weight	300.33 g/mol
Synonyms	1-Tosyl-1H-pyrrolo[2,3-b]pyridine-2-carboxaldehyde; 1-[(4-Methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde; 1-(p-Toluenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxaldehyde; 1-Tosyl-7-azaindole-2-carboxaldehyde; 1H-Pyrrolo[2,3-b]pyridine-2-carboxaldehyde, 1-[(4-methylphenyl)sulfonyl]-; 479553-03-2; 1-Ts-7-azaindole-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxaldehyde, 1-[(4-Methylphenyl)Sulfonyl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.