Description

2-(E)-Benzylidene-6-(Trifluoroacetyl)Cyclohexanone is a high-value synthetic intermediate characterized by its unique α,β-unsaturated ketone structure functionalized with a trifluoroacetyl group. This compound is critical for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules due to its reactive carbonyl and alkene functionalities. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the research of specialty polymers and advanced organic materials.
• Chemical Synthesis: Employed in academic and industrial laboratories for methodological studies, including Michael additions, cyclization reactions, and as a precursor for heterocyclic compounds.
• Fluorine Chemistry Studies: A valuable substrate for investigating the influence of fluorine atoms on chemical reactivity and physical properties in organic molecules.

Basic Information

Product Name	2-(E)-Benzylidene-6-(Trifluoroacetyl)Cyclohexanone
CAS No.	479499-02-0
Molecular Formula	C16H13F3O2
Molecular Weight	294.27 g/mol
Synonyms	(E)-2-Benzylidene-6-(trifluoroacetyl)cyclohexan-1-one; 2-Benzylidene-6-(2,2,2-trifluoroacetyl)cyclohexanone; 6-(Trifluoroacetyl)-2-benzylidenecyclohexanone; 2-(Benzylidene)-6-(trifluoroacetyl)cyclohexanone; 479499-02-0; Cyclohexanone, 2-(phenylmethylene)-6-(trifluoroacetyl)-, (E)-
EINECS	Contact for details

Quality Control

Every batch of 2-(E)-Benzylidene-6-(Trifluoroacetyl)Cyclohexanone is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.