Description

2-(2,5-Dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS NO 479411-91-1 is a high-purity, pinacol-protected boronic ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, where it is used to develop novel active ingredients and functional organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing substituted biphenyl or heteroaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific chlorinated aryl structures.
• Material Science & OLED Development: Enables the creation of novel organic semiconductors, light-emitting materials, and liquid crystals through precise cross-coupling.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic pathways and complex molecule construction.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Polymer Chemistry: Can be incorporated into polymer backbones to create functional materials with tailored electronic or physical properties.

Basic Information

Product Name	2-(2,5-Dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.	479411-91-1
Molecular Formula	C12H15BCl2O2
Molecular Weight	273.96 g/mol
Synonyms	(2,5-Dichlorophenyl)boronic acid pinacol ester; 2,5-Dichlorophenylboronic acid pinacol ester; Pinacol (2,5-dichlorophenyl)boronate; 2-(2,5-Dichlorophenyl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; (2,5-Dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-(2,5-Dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2,5-Dichlorobenzene boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.