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Methyl 2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetate CAS NO 478375-42-7
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CAS No.:478375-42-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Methyl 2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetate is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a protected boronic acid, offering enhanced stability and solubility for key cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for complex molecule synthesis.
Application
- Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl motifs found in active pharmaceutical ingredients (APIs).
- Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific phenylacetic acid derivatives.
- Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
- Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
- Chemical Biology Probes: Utilized in the synthesis of tagged molecules and probes for studying biological processes.
- Custom Synthesis and R&D: A versatile building block for contract research organizations and academic laboratories exploring new chemical entities.
Basic Information
| Product Name | Methyl 2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetate |
| CAS No. | 478375-42-7 |
| Molecular Formula | C15H21BO4 |
| Molecular Weight | 276.14 g/mol |
| Synonyms | [3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetic acid methyl ester; Methyl (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzeneacetic acid methyl ester; Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylacetate; Boronic acid, B-[3-(methoxycarbonylmethyl)phenyl]-, 1,3-propanediol ester; Pinacol ester of 3-(Methoxycarbonylmethyl)phenylboronic acid |
| EINECS | Contact for details |
Quality Control
Our Methyl 2-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed to protect from moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Assay (HPLC) | ≥97.0% |
| Purity (GC) | ≥98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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