Description

Dichloro[(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-Bis(Di(3,5-Xylyl)Phosphino)-3,3'-Bipyridine][(1R,2R)-(+)-1,2-Diphenylethylenediamine]Ruthenium (Ii) is a highly specialized chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a precise and efficient catalyst for enantioselective hydrogenation and other critical synthetic transformations. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of chiral active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral ketones, olefins, and imines in pharmaceutical synthesis.
• Chiral Intermediate Production: In the manufacture of enantiomerically pure compounds for drug discovery and development.
• Fine Chemical Synthesis: For creating high-value, complex molecules in agrochemical and specialty chemical research.
• Academic & Industrial Research: As a key reagent in methodological studies and process optimization for catalytic reactions.
• Ligand-Metal Complex Studies: For investigating structure-activity relationships in chiral phosphine-based catalyst systems.

Basic Information

Product Name	Dichloro[(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-Bis(Di(3,5-Xylyl)Phosphino)-3,3'-Bipyridine][(1R,2R)-(+)-1,2-Diphenylethylenediamine]Ruthenium (Ii)
CAS No.	478308-93-9
Molecular Formula	C72H74Cl2N4O4P2Ru
Molecular Weight	1252.70 g/mol
Synonyms	Ru-Mandyphos-DPEN Complex; Dichloro[(R)-(+)-Mandyphos][(1R,2R)-DPEN]Ruthenium(II); (R,R)-Ru-Mandyphos-DPEN Catalyst; Ruthenium(II) dichloro[(R)-2,2',6,6'-tetramethoxy-4,4'-bis(di-3,5-xylylphosphino)-3,3'-bipyridine][(1R,2R)-1,2-diphenylethylenediamine]; Asymmetric Hydrogenation Catalyst 478308-93-9; (R,R)-Ru-Mandyphos-(R,R)-DACH (common misnomer); Chiral Ru-Phosphine-Diamine Complex
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and catalytic activity. Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay, chiral purity, and residual solvent content. We adhere to strict internal quality protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at a controlled room temperature (15-25°C). This compound is easily oxidized and light-sensitive; prolonged exposure to air or light may degrade its catalytic performance.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Chiral Purity (HPLC)	≥99.0% ee
Residual Solvents (GC)	Meet ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.