Description

2-[(3,4,4-Trifluorobut-3-En-1-Yl)Thio]Nicotinohydrazide is a high-value, specialized organic compound featuring a unique trifluorobutene-thioether linkage to a nicotinohydrazide core. This molecular architecture makes it a critical advanced pharmaceutical intermediate for the research and development of novel active ingredients. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex, fluorinated drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting fluorinated molecules.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental stability.
• Chemical Biology Probe: Acts as a precursor for creating specialized probes to study enzyme interactions and biological pathways due to its reactive hydrazide group.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with specific surface or thermal properties.
• Organic Synthesis Reagent: Employed in advanced organic synthesis for constructing complex heterocyclic compounds and fluorinated structures.

Basic Information

Product Name	2-[(3,4,4-Trifluorobut-3-En-1-Yl)Thio]Nicotinohydrazide
CAS No.	478247-67-5
Molecular Formula	C10H9F3N3OS
Molecular Weight	276.26 g/mol
Synonyms	2-[(3,4,4-Trifluorobut-3-en-1-yl)sulfanyl]pyridine-3-carbohydrazide; Nicotinohydrazide, 2-[(3,4,4-trifluoro-3-buten-1-yl)thio]-; 2-((3,4,4-Trifluorobut-3-en-1-yl)thio)nicotinohydrazide; 3-Pyridinecarboxylic acid, 2-[(3,4,4-trifluoro-3-buten-1-yl)thio]-, hydrazide; 478247-67-5; 2-[(3,4,4-Trifluorobut-3-enyl)thio]nicotinic acid hydrazide
EINECS	Contact for details

Quality Control

Our 2-[(3,4,4-Trifluorobut-3-En-1-Yl)Thio]Nicotinohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.