Description

4-(2,6-Difluorophenyl)-4-Oxobutyric Acid is a high-purity organic building block featuring a difluorophenyl ketone moiety linked to a butyric acid chain. This compound is valued for its role as a versatile synthetic intermediate in the development of advanced pharmaceutical and agrochemical molecules. It is primarily sought by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing complex target structures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, leveraging the stability imparted by the fluorine atoms.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in the development of advanced polymers and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in medicinal chemistry for creating tool compounds and probes to study enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-(2,6-Difluorophenyl)-4-Oxobutyric Acid
CAS No.	478162-62-8
Molecular Formula	C10H8F2O3
Molecular Weight	214.17 g/mol
Synonyms	4-Oxo-4-(2,6-difluorophenyl)butanoic acid; 2,6-Difluoro-γ-oxobenzenebutanoic acid; γ-Oxo-2,6-difluorobenzenebutanoic acid; 4-(2,6-Difluorobenzoyl)butyric acid; Butanoic acid, 4-oxo-4-(2,6-difluorophenyl)-; 478162-62-8
EINECS	Contact for details

Quality Control

Our production of 4-(2,6-Difluorophenyl)-4-Oxobutyric Acid adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.