Description

(E)-1-(2-Naphthyl)-3-[4-(Trifluoromethoxy)Anilino]-2-Buten-1-One is a specialized organic intermediate featuring a conjugated enone system linked to naphthyl and trifluoromethoxy-substituted anilino groups. This compound matters for its role as a key building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique structure imparts specific electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced organic electronics industries.

Application

• Pharmaceutical intermediate for the development of novel small-molecule therapeutics.
• Key precursor in the synthesis of advanced organic electronic materials, such as OLED emitters or charge transport layers.
• Building block for agrochemical research, particularly in creating compounds with enhanced biological activity and environmental stability.
• Versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Intermediate for specialty dyes and pigments leveraging the naphthalene chromophore.
• Research chemical for studying photophysical properties and reaction mechanisms of complex enones.

Basic Information

Product Name	(E)-1-(2-Naphthyl)-3-[4-(Trifluoromethoxy)Anilino]-2-Buten-1-One
CAS No.	478041-00-8
Molecular Formula	C21H16F3NO2
Molecular Weight	371.35 g/mol
Synonyms	1-(2-Naphthyl)-3-[4-(trifluoromethoxy)anilino]-2-buten-1-one; (E)-1-(Naphthalen-2-yl)-3-{[4-(trifluoromethoxy)phenyl]amino}but-2-en-1-one; 3-[4-(Trifluoromethoxy)anilino]-1-(2-naphthyl)-2-buten-1-one; 478041-00-8; N-(4-(Trifluoromethoxy)phenyl)-3-oxo-3-(2-naphthyl)-1-propen-1-amine; Enaminone derivative CAS 478041-00-8
EINECS	Contact for details

Quality Control

Our (E)-1-(2-Naphthyl)-3-[4-(Trifluoromethoxy)Anilino]-2-Buten-1-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.