Description

Ethyl 3-(3-Chlorophenyl)-1,2,4-oxadiazole-5-carboxylate is a high-value, heterocyclic organic compound featuring a 1,2,4-oxadiazole core substituted with a 3-chlorophenyl group and an ethyl ester moiety. This specialized chemical serves as a critical building block (synthon) and key intermediate in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, particularly those targeting neurological disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the 1,2,4-oxadiazole scaffold.
• Material Science: Serves as a monomer or functional component in the research of advanced polymers and liquid crystals.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in biochemical research due to its specific reactivity.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.
• Fine Chemical Synthesis: A versatile building block for creating complex esters, amides, and other derivatives with tailored properties.

Basic Information

Product Name	Ethyl 3-(3-Chlorophenyl)-1,2,4-oxadiazole-5-carboxylate
CAS No.	478030-49-8
Molecular Formula	C11H9ClN2O3
Molecular Weight	252.65 g/mol
Synonyms	5-Ethoxycarbonyl-3-(3-chlorophenyl)-1,2,4-oxadiazole; Ethyl 3-(3-chlorophenyl)-1,2,4-oxadiazole-5-carboxylate; 1,2,4-Oxadiazole-5-carboxylic acid, 3-(3-chlorophenyl)-, ethyl ester; 3-(3-Chlorophenyl)-1,2,4-oxadiazole-5-carboxylic acid ethyl ester; 3-(3-Chlorophenyl)-5-(ethoxycarbonyl)-1,2,4-oxadiazole; 478030-49-8; 3-(3-Chlorophenyl)-1,2,4-oxadiazole-5-carboxylic acid, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(3-Chlorophenyl)-1,2,4-oxadiazole-5-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.