Description

(E)-1-[4-(3-Fluoropropoxy)Phenyl]-3-(3-Toluidino)-2-Propen-1-One is a high-purity, synthetic organic compound featuring a chalcone-like structure with a fluoropropoxy substituent. This compound is valued for its role as a versatile chemical intermediate in advanced pharmaceutical and agrochemical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and life science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and inflammatory pathways.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its unique fluorinated side chain for enhanced bioactivity and environmental stability.
• Chemical Biology Probe: Serves as a core scaffold for developing fluorescent probes or enzyme inhibitors to study biological processes in academic and industrial research settings.
• Material Science Precursor: Acts as a monomer or precursor for advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) or semiconductors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated chalcone derivatives.

Basic Information

Product Name	(E)-1-[4-(3-Fluoropropoxy)Phenyl]-3-(3-Toluidino)-2-Propen-1-One
CAS No.	477889-22-8
Molecular Formula	C19H20FNO2
Molecular Weight	313.37 g/mol
Synonyms	(E)-1-[4-(3-Fluoropropoxy)phenyl]-3-(3-methylphenylamino)prop-2-en-1-one; 3'-Methyl-4'-(3-fluoropropoxy)chalcone; 1-[4-(3-Fluoropropoxy)phenyl]-3-[(3-methylphenyl)amino]-2-propen-1-one; (E)-3-(3-Toluidino)-1-[4-(3-fluoropropoxy)phenyl]-2-propen-1-one; 477889-22-8; 4'-(3-Fluoropropoxy)-3'-methylchalcone; Fluorinated Chalcone Derivative
EINECS	Contact for details

Quality Control

Our (E)-1-[4-(3-Fluoropropoxy)Phenyl]-3-(3-Toluidino)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.