Description

2-[(3-Chlorophenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile is a high-value, multi-functional organic intermediate featuring a benzenecarbonitrile core substituted with a trifluoromethyl group and a 3-chlorophenylsulfanyl moiety. This compound matters for its role as a critical building block in advanced chemical synthesis, enabling the introduction of both sulfur and fluorine-containing pharmacophores. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, or insecticides that leverage the trifluoromethyl group for enhanced bioactivity and environmental stability.
• Material Science Research: Used in the development of advanced organic electronic materials, such as semiconductors or liquid crystals, where the specific electronic properties of the molecule are exploited.
• Ligand and Catalyst Development: The sulfur and nitrile functionalities make it a candidate for constructing novel ligands in transition metal catalysis or organocatalysis.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, proprietary synthesis projects.

Basic Information

Product Name	2-[(3-Chlorophenyl)Sulfanyl]-5-(Trifluoromethyl)Benzenecarbonitrile
CAS No.	477866-76-5
Molecular Formula	C14H7ClF3NS
Molecular Weight	313.72 g/mol
Synonyms	2-[(3-Chlorophenyl)thio]-5-(trifluoromethyl)benzonitrile; 5-(Trifluoromethyl)-2-[(3-chlorophenyl)thio]benzonitrile; 2-(3-Chlorophenylsulfanyl)-5-trifluoromethylbenzonitrile; Benzonitrile, 2-[(3-chlorophenyl)thio]-5-(trifluoromethyl)-; 2-(3-Chlorophenylthio)-5-(trifluoromethyl)benzonitrile; 477866-76-5; 2-(3-Chlorophenylsulfanyl)-5-(trifluoromethyl)benzonitrile
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for fine chemical intermediates. Every batch is characterized using advanced analytical techniques to confirm identity and purity. Certificates of Analysis (COA) are provided, detailing key parameters such as assay, impurity profile, and physical properties. We adhere to a cGMP-compliant quality management system where applicable, ensuring traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.