Description

1-[3A,11C-Dihydro-3H-Benzo[5,6]Chromeno[4,3-C]Isoxazol-1(4H)-Yl]-2-Chloro-1-Ethanone is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring precise and reliable building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Oncology Drug Development: Employed in the construction of molecules designed as kinase inhibitors or targeted cancer therapies.
• CNS-Active Compound Synthesis: A building block for developing potential treatments for neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized to create tool compounds for studying enzyme function and cellular processes.
• Academic & Institutional Research: Supports fundamental research in organic synthesis and heterocyclic chemistry at universities and institutes.

Basic Information

Product Name	1-[3A,11C-Dihydro-3H-Benzo[5,6]Chromeno[4,3-C]Isoxazol-1(4H)-Yl]-2-Chloro-1-Ethanone
CAS No.	477853-77-3
Molecular Formula	C₁₈H₁₄ClNO₃
Molecular Weight	327.76 g/mol
Synonyms	2-Chloro-1-[1,4-dihydro-3H-benzo[5,6]chromeno[4,3-c]isoxazol-1-yl]ethanone; 1-(1,4-Dihydro-3H-benzo[5,6]chromeno[4,3-c]isoxazol-1-yl)-2-chloroethan-1-one; 2-Chloro-1-(1,4-dihydro-3H-benzo[5,6]chromeno[4,3-c]isoxazol-1-yl)ethanone; Benzo[5,6]chromeno[4,3-c]isoxazole ethanone derivative; Chromenoisoxazolyl Chloroethanone
EINECS	Contact for details

Quality Control

Our 1-[3A,11C-Dihydro-3H-Benzo[5,6]Chromeno[4,3-C]Isoxazol-1(4H)-Yl]-2-Chloro-1-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.