Description

(E)-3-(2-Chloro-6-Fluorophenyl)-1-(4-Methyl-2-Phenyl-1,3-Thiazol-5-Yl)-2-Propen-1-One is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active molecules. This compound is critical for research and development in medicinal chemistry, offering a precise structural scaffold for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in areas requiring specific halogenated and heterocyclic architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and validation in QC laboratories.
• Agrochemical Research: Potential intermediate for the development of new crop protection agents and pesticides.
• Material Science Precursor: Can be investigated for the synthesis of specialized organic materials and ligands for catalysis.

Basic Information

Product Name	(E)-3-(2-Chloro-6-Fluorophenyl)-1-(4-Methyl-2-Phenyl-1,3-Thiazol-5-Yl)-2-Propen-1-One
CAS No.	477847-71-5
Molecular Formula	C19H13ClFNOS
Molecular Weight	357.83 g/mol
Synonyms	(E)-3-(2-Chloro-6-fluorophenyl)-1-(4-methyl-2-phenylthiazol-5-yl)prop-2-en-1-one; 2-Propen-1-one, 3-(2-chloro-6-fluorophenyl)-1-(4-methyl-2-phenyl-5-thiazolyl)-, (E)-; 477847-71-5; (E)-1-(4-Methyl-2-phenyl-1,3-thiazol-5-yl)-3-(2-chloro-6-fluorophenyl)prop-2-en-1-one; Chalcone derivative, halogenated thiazole; 5-[(1E)-3-(2-Chloro-6-fluorophenyl)-3-oxo-1-propen-1-yl]-4-methyl-2-phenylthiazole
EINECS	Contact for details

Quality Control

Our (E)-3-(2-Chloro-6-Fluorophenyl)-1-(4-Methyl-2-Phenyl-1,3-Thiazol-5-Yl)-2-Propen-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.