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4-Bromobenzylboronic Acid Pinacol Ester CAS NO 477841-90-0


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CAS No.:477841-90-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Bromobenzylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound matters for its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and conjugated systems. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly those containing biphenyl or substituted benzyl motifs.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific halogenated aromatic structures.
  • Material Science Research: Serves as a monomer or precursor in the creation of organic electronic materials, such as OLEDs and semiconductors.
  • Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organometallic chemistry.
  • Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
  • Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates on a commercial scale.

Basic Information

Product Name 4-Bromobenzylboronic Acid Pinacol Ester
CAS No. 477841-90-0
Molecular Formula C13H18BBrO2
Molecular Weight 297.00 g/mol
Synonyms 4-Bromobenzylboronic Acid Pinacol Ester; (4-Bromobenzyl)boronic Acid Pinacol Ester; 2-(4-Bromobenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-(4-Bromobenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Bromobenzylboronic Acid, Pinacol Ester; 4-Bromobenzyl-Bpin; 1-Bromo-4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)benzene
EINECS Contact for details

Quality Control

Our 4-Bromobenzylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and prevent hydrolysis.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0%
Purity (NMR) ≥97.0%
Melting Point Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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