Description

Benzoic Acid, 4-(Formylamino)-, 1,1-Dimethylethyl Ester is a specialized benzoic acid derivative, specifically an N-formyl tert-butyl ester, that serves as a valuable protected intermediate in advanced organic synthesis. This compound is crucial for researchers and manufacturers requiring precise control over amino group reactivity during multi-step synthetic sequences. It is primarily utilized in the development of pharmaceuticals, agrochemicals, and other fine chemicals where the tert-butyloxycarbonyl (Boc) and formyl protecting groups are strategically employed.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing protected aniline functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific amino acid derivatives.
• Peptide Chemistry: Serves as a protected amino acid analog in peptide coupling reactions and solid-phase peptide synthesis (SPPS).
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecular architectures, leveraging its orthogonal protecting groups.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and functional organic materials.

Basic Information

Product Name	Benzoic Acid, 4-(Formylamino)-, 1,1-Dimethylethyl Ester
CAS No.	477721-50-9
Molecular Formula	C13H17NO3
Molecular Weight	235.28 g/mol
Synonyms	tert-Butyl 4-formamidobenzoate; 4-(Formylamino)benzoic Acid tert-Butyl Ester; 4-Formamidobenzoic Acid tert-Butyl Ester; N-Formyl-4-aminobenzoic Acid tert-Butyl Ester; Benzoic acid, 4-(formylamino)-, 1,1-dimethylethyl ester; tert-Butyl N-formyl-4-aminobenzoate; 4-(N-Formylamino)benzoic Acid t-Butyl Ester
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-(Formylamino)-, 1,1-Dimethylethyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements. We adhere to cGMP principles for production relevant to pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.