Description

1-Piperidineacetonitrile,4-Fluoro-(9Ci) is a specialized fluorinated piperidine derivative, a high-value intermediate in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which incorporates both a nitrile group and a fluorine atom on the piperidine ring, enabling precise structural modifications for developing novel compounds. This product is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a critical building block for creating new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and other bioactive molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atom can improve metabolic stability and bioavailability.
• Chemical Biology Probe Synthesis: Employed to create fluorinated analogs for studying enzyme mechanisms and protein-ligand interactions.
• Material Science: Serves as a monomer or functionalization agent in the research of specialty polymers and advanced materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific fluorinated heterocyclic architectures.

Basic Information

Product Name	1-Piperidineacetonitrile,4-Fluoro-(9Ci)
CAS No.	477576-96-8
Molecular Formula	C7H11FN2
Molecular Weight	142.18 g/mol
Synonyms	4-Fluoro-1-piperidineacetonitrile; 4-Fluoropiperidine-1-acetonitrile; (4-Fluoropiperidin-1-yl)acetonitrile; 1-(Cyanomethyl)-4-fluoropiperidine; 4-Fluoro-piperidine-1-acetic acid nitrile; 477576-96-8; 4-Fluoro-1-piperidineacetonitrile (9CI)
EINECS	Contact for details

Quality Control

Every batch of 1-Piperidineacetonitrile,4-Fluoro-(9Ci) is produced and tested under a strict quality management system. We ensure compliance with the high-purity standards required for research and pharmaceutical intermediate applications. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.