Description

1-(4-Bromophenyl)-3-(4-Fluoroanilino)-1-Propanone is a high-purity organic intermediate featuring a unique bromo- and fluoro-substituted aromatic ketone structure. This compound is valued for its role as a versatile building block in advanced organic synthesis, enabling the introduction of specific halogenated motifs into target molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the bromophenyl and fluoroanilino groups contribute to biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probe Synthesis: Employed to create molecular probes for studying enzyme mechanisms or protein-ligand interactions due to its modifiable ketone and amine functionalities.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces in heterocyclic and medicinal chemistry.

Basic Information

Product Name	1-(4-Bromophenyl)-3-(4-Fluoroanilino)-1-Propanone
CAS No.	477320-45-9
Molecular Formula	C15H13BrFNO
Molecular Weight	322.17 g/mol
Synonyms	1-Propanone, 1-(4-bromophenyl)-3-[(4-fluorophenyl)amino]-; 3-[(4-Fluorophenyl)amino]-1-(4-bromophenyl)-1-propanone; 1-(4-Bromophenyl)-3-(4-fluoroanilino)propan-1-one; N-(4-Fluorophenyl)-3-(4-bromobenzoyl)propylamine
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Bromophenyl)-3-(4-Fluoroanilino)-1-Propanone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your R&D and scale-up processes. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.