Description

(S)-Boroleu-(-)-Pinanediol-Cf3Cooh CAS NO 477254-69-6 is a high-purity, chiral organoboron reagent featuring a pinanediol protecting group and a trifluoroacetic acid moiety. This compound is valued for its role as a key synthetic intermediate in the production of complex, optically active molecules, particularly in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Used in Suzuki-Miyaura and other cross-coupling reactions to introduce chiral boronic ester functionalities with high enantiomeric purity.
• Agrochemical Research: Serves as a precursor for developing novel, chiral herbicides and pesticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the preparation of novel chiral ligands and catalysts for homogeneous catalysis.
• Material Science: A precursor for boron-containing polymers and advanced organic electronic materials.
• Academic & Contract Research: Essential for methodological development in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Item	Details
Product Name	(S)-Boroleu-(-)-Pinanediol-Cf3Cooh
CAS No.	477254-69-6
Molecular Formula	C₁₇H₂₆BF₃O₄
Molecular Weight	362.20 g/mol
Synonyms	(S)-(-)-Pinanediol Trifluoroborate Leucinate; (S)-Leucine Trifluoroboronate Pinanediol Ester; (S)-N-((Trifluoroboranyl)leucinyl)pinanediol; Leucine Trifluoroboronic Acid Pinanediol Ester (S-isomer); (S)-α-Amino-γ-methylvaleric Acid Trifluoroboron Pinacol Ester; Boron-Leucine-CF3-Pinanediol Complex; (S)-BoroLeu(CF3COOH)Pinanediol
EINECS	Contact for details

Quality Control

Our production of (S)-Boroleu-(-)-Pinanediol-Cf3Cooh adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity, critical for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain stability and purity. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.