Description

5-(Methylthio)Pyridine-3-Boronic Acid is a versatile organoboron building block, specifically a pyridine-substituted boronic acid derivative. This compound is a critical intermediate in modern synthetic chemistry, enabling the formation of carbon-carbon bonds via cross-coupling reactions. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and fungicides, leveraging its structural motif for bioactivity.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials through Suzuki-Miyaura cross-coupling.
• Chemical Biology & Proteomics: Employed in the development of molecular probes, bioconjugation reagents, and tools for studying biological systems.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific boronic acid derivatives.

Basic Information

Product Name	5-(Methylthio)Pyridine-3-Boronic Acid
CAS No.	477251-98-2
Molecular Formula	C7H8BNO2S
Molecular Weight	168.99 g/mol
Synonyms	5-(Methylthio)-3-pyridineboronic acid; (5-(Methylthio)pyridin-3-yl)boronic acid; 3-Borono-5-(methylthio)pyridine; 5-Methylsulfanylpyridine-3-boronic acid; 5-(Methylmercapto)pyridine-3-boronic acid; 5-(Methylsulfanyl)pyridine-3-boronic acid; 5-(Methylthio)-3-pyridinylboronic acid; 5-Methylthiopyridine-3-boronic Acid
EINECS	Contact for details

Quality Control

Our 5-(Methylthio)Pyridine-3-Boronic Acid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation upon opening.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.