Description

1(2H)-Naphthalenone, 3,4-Dihydro-2-Hydroxy-6-Methoxy-4,7-Dimethyl-, (2S,4R)- (9Ci) is a chiral, stereochemically defined naphthalenone derivative that serves as a valuable synthetic intermediate and building block in advanced organic chemistry. Its specific stereochemistry and functional group arrangement make it a critical precursor for the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, structurally precise intermediates for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and other high-value specialty chemicals requiring defined molecular architecture.
• Academic & R&D: Employed in university and corporate laboratories for methodological studies in asymmetric synthesis and natural product analog development.
• Material Science Research: Potential monomer or precursor for designing organic electronic materials or liquid crystals due to its rigid, fused-ring structure.

Basic Information

Product Name	1(2H)-Naphthalenone, 3,4-Dihydro-2-Hydroxy-6-Methoxy-4,7-Dimethyl-, (2S,4R)- (9Ci)
CAS No.	477199-83-0
Molecular Formula	C₁₃H₁₆O₃
Molecular Weight	220.27 g/mol
Synonyms	(2S,4R)-3,4-Dihydro-2-hydroxy-6-methoxy-4,7-dimethyl-1(2H)-naphthalenone; (2S,4R)-2-Hydroxy-6-methoxy-4,7-dimethyl-3,4-dihydro-1(2H)-naphthalenone; (2S,4R)-2-Hydroxy-6-methoxy-4,7-dimethyl-3,4-dihydronaphthalen-1(2H)-one; 2-Hydroxy-6-methoxy-4,7-dimethyl-1-tetralone (stereospecific); (2S,4R)-HMDN; Light-sensitive (store away from light) tetralone derivative.
EINECS	Contact for details

Quality Control

Our 1(2H)-Naphthalenone, 3,4-Dihydro-2-Hydroxy-6-Methoxy-4,7-Dimethyl-, (2S,4R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.