Description

4-Methylthiophene-3-Boronic Acid Pinacol Ester is a high-purity organoboron building block essential for modern synthetic chemistry. This compound is a critical reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly those containing functionalized thiophene cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with tailored properties.
• Material Science: Employed in the creation of organic electronic materials, such as semiconductors for OLEDs and OFETs.
• Chemical Research: Serves as a versatile coupling partner in academic and industrial laboratories for methodology development and library synthesis.
• Ligand & Catalyst Development: Used to construct complex ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	4-Methylthiophene-3-Boronic Acid Pinacol Ester
CAS No.	476620-20-9
Molecular Formula	C11H17BO2S
Molecular Weight	224.13 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methylthiophene; 4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; 4-Methylthiophene-3-boronic acid pinacol ester; 4-Methyl-3-thienylboronic acid pinacol ester; 3-Borono-4-methylthiophene pinacol ester; Pinacol 4-Methyl-3-thienylboronate
EINECS	Contact for details

Quality Control

Our 4-Methylthiophene-3-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (by HPLC/NMR). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system supports traceability for all materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive nature. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.