Description

2-(4-Fluorophenyl)-1-(6-Methylpyridine-2-Yl)Ethanone is a high-purity, specialized organic compound featuring a fluorinated phenyl ring and a methylated pyridine moiety. This unique structure makes it a valuable key intermediate for advanced chemical synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating novel therapeutic agents and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and material science applications.
• Organic Electronic Materials: A potential component in the research and development of organic semiconductors and light-emitting materials.
• Chemical Biology Probes: Employed in the design of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	2-(4-Fluorophenyl)-1-(6-Methylpyridine-2-Yl)Ethanone
CAS No.	476472-56-7
Molecular Formula	C14H12FNO
Molecular Weight	229.25 g/mol
Synonyms	1-(6-Methyl-2-pyridinyl)-2-(4-fluorophenyl)ethanone; 2-(4-Fluorophenyl)-1-(6-methyl-2-pyridinyl)ethan-1-one; 2-Acetyl-6-methylpyridine 4-fluorobenzyl ketone; 4'-Fluoro-2',6'-dimethylacetophenone pyridine derivative; (4-Fluorophenyl)(6-methylpyridin-2-yl)methanone (tautomeric form); FMPE Intermediate; CAS 476472-56-7
EINECS	Contact for details

Quality Control

Our production of 2-(4-Fluorophenyl)-1-(6-Methylpyridine-2-Yl)Ethanone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous demands of GMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.