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1-(3-Fluorophenyl)-2-(4-Fluorophenyl)Ethanone CAS NO 476472-53-4


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CAS No.:476472-53-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(3-Fluorophenyl)-2-(4-Fluorophenyl)Ethanone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its difluorinated biphenyl-like core imparts specific electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate fluorinated motifs into novel molecular architectures.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
  • Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides where fluorine atoms enhance biological activity and environmental stability.
  • Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated mesogens and electron-transport materials in display and lighting technologies.
  • Organic Ligand Preparation: Utilized for constructing sophisticated ligands in catalysis and metal-organic frameworks (MOFs).
  • Academic & Contract Research: A valuable reagent for methodological studies in cross-coupling and fluorination chemistry within university and CRO laboratories.
  • Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name 1-(3-Fluorophenyl)-2-(4-Fluorophenyl)Ethanone
CAS No. 476472-53-4
Molecular Formula C14H10F2O
Molecular Weight 232.23 g/mol
Synonyms 3',4'-Difluorobenzophenone; 1-(3-Fluorophenyl)-2-(4-fluorophenyl)ethan-1-one; 3-Fluoro-4'-fluorobenzophenone; (3-Fluorophenyl)(4-fluorophenyl)methanone; 3,4'-Difluorobenzophenone; α,α-Bis(fluorophenyl)ketone; DFBP
EINECS Contact for details

Quality Control

Our 1-(3-Fluorophenyl)-2-(4-Fluorophenyl)Ethanone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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