Description

2-Quinolin-4-Yl-1-[4-(Trifluoromethyl)Phenyl]Ethanone is a high-value, fluorinated organic building block featuring a quinoline core and a trifluoromethylphenyl ketone moiety. This compound is critical for advanced research and development, particularly in the synthesis of novel pharmacologically active molecules and functional materials. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers for creating compounds with enhanced biological activity and specific physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors, anti-cancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Material Science Research: Serves as a precursor for developing organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Utilized in designing fluorescent probes or affinity tags for studying biological processes and protein interactions.
• Catalyst Ligand Synthesis: Acts as a starting material for synthesizing novel chiral or achiral ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	2-Quinolin-4-Yl-1-[4-(Trifluoromethyl)Phenyl]Ethanone
CAS No.	476472-22-7
Molecular Formula	C₁₈H₁₂F₃NO
Molecular Weight	315.29 g/mol
Synonyms	4-(4-(Trifluoromethyl)benzoyl)quinoline; 1-[4-(Trifluoromethyl)phenyl]-2-(quinolin-4-yl)ethanone; 2-(4-Quinolinyl)-1-[4-(trifluoromethyl)phenyl]ethanone; 4-(4-Trifluoromethylbenzoyl)quinoline; Ethanone, 2-(4-quinolinyl)-1-[4-(trifluoromethyl)phenyl]-; CAS 476472-22-7
EINECS	Contact for details

Quality Control

Our 2-Quinolin-4-Yl-1-[4-(Trifluoromethyl)Phenyl]Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.