Description

(R)-Borophg(+)-Pinanediol-Hcl is a high-purity chiral boronic ester derivative, serving as a critical intermediate in asymmetric synthesis. Its value lies in providing a stereochemically defined boron center, enabling precise carbon-boron bond formation for the construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral drug candidates, especially those requiring Suzuki-Miyaura cross-coupling reactions.
• Asymmetric Catalysis: Used as a chiral ligand precursor or reagent in catalytic cycles to induce enantioselectivity.
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing complex, stereodefined organic architectures.
• Agrochemical Development: Intermediate in the synthesis of chiral, biologically active compounds for crop protection.
• Material Science: Potential precursor for boron-containing polymers or advanced functional materials.

Basic Information

Product Name	(R)-Borophg(+)-Pinanediol-Hcl
CAS No.	476334-31-3
Molecular Formula	C₁₆H₂₈BClO₂
Molecular Weight	298.66 g/mol
Synonyms	(R)-(-)-2-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzo[h]quinoline Hydrochloride; (R)-Borophg Pinanediol Ester Hydrochloride; (R)-BoroPhg(Me) Pinanediol HCl; (R)-2-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzo[h]quinoline HCl; Benzo[h]quinolin-2-ylboronic acid pinanediol ester hydrochloride, (R)-; (R)-Borophg Pinacol Ester Hydrochloride (common misnomer)
EINECS	Contact for details

Quality Control

Every batch of (R)-Borophg(+)-Pinanediol-Hcl is produced under strict quality management systems. We ensure compliance with high-purity standards suitable for research and cGMP manufacturing applications. Comprehensive analytical testing, including HPLC for chiral purity and assay, is performed. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.