Description

Benzene, 1-Ethoxy-4-(2,2,2-Trifluoroethyl)- (9Ci) is a specialized fluorinated aromatic ether building block, identified by CAS number 476300-58-0. This compound is valued for its unique chemical structure, which combines an ethoxy group and a trifluoroethyl moiety on a benzene ring, making it a versatile intermediate for advanced synthesis. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoroethyl group can impart improved activity and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Specialty Polymer Modifier: Incorporated into polymer chains to alter surface properties, chemical resistance, or optical characteristics.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecules via cross-coupling and functional group transformation reactions.
• Fluorine Chemistry Research: A valuable compound for studying structure-activity relationships and the effects of fluorine substitution in aromatic systems.

Basic Information

Product Name	Benzene, 1-Ethoxy-4-(2,2,2-Trifluoroethyl)- (9Ci)
CAS No.	476300-58-0
Molecular Formula	C10H11F3O
Molecular Weight	204.19 g/mol
Synonyms	1-Ethoxy-4-(2,2,2-trifluoroethyl)benzene; p-Ethoxy(2,2,2-trifluoroethyl)benzene; 4-Ethoxy-α,α,α-trifluorotoluene; 2,2,2-Trifluoro-1-(4-ethoxyphenyl)ethane; 4-(2,2,2-Trifluoroethyl)phenetole; 1-Ethoxy-4-(trifluoroethyl)benzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-Ethoxy-4-(2,2,2-Trifluoroethyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for research and commercial-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.