Description

2-Pinacolateborylpyrrole is a specialized organoboron reagent featuring a pinacol-protected boronic ester group attached to a pyrrole heterocycle. This compound is a critical building block in modern synthetic chemistry, enabling the efficient construction of complex molecules through cross-coupling reactions. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between the pyrrole ring and aryl/heteroaryl halides, essential for synthesizing complex biaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly those containing pyrrole or indole-like pharmacophores.
• Agrochemical Synthesis: Serves as a precursor in creating new active ingredients for crop protection products.
• Material Science & Organic Electronics: A building block for constructing conjugated organic molecules used in OLEDs, organic semiconductors, and sensors.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and labeled compounds for biological studies.
• Catalyst & Ligand Development: Can be incorporated into novel ligand frameworks for transition metal catalysis.

Basic Information

Product Name	2-Pinacolateborylpyrrole
CAS No.	476004-79-2
Molecular Formula	C14H20BNO2
Molecular Weight	245.13 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole; Pyrrole-2-boronic acid pinacol ester; 2-Pyrrolylboronic acid pinacol ester; 2-Boronopyrrole pinacol ester; 2-Pinacolborylpyrrole; 2-Pyrroleboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 2-Pinacolateborylpyrrole is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot is analyzed via NMR, HPLC, and other spectroscopic techniques to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.