Description

4-Methoxybenzylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl or vinyl halides and boronic acids, fundamental in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Used in the research and scale-up production of active pharmaceutical ingredients (APIs), especially those containing methoxybenzyl motifs.
• Agrochemical Development: Employed in creating novel herbicides, fungicides, and insecticides with tailored properties.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Incorporated into the synthesis of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and activity-based protein profiling (ABPP) reagents.

Basic Information

Product Name	4-Methoxybenzylboronic Acid Pinacol Ester
CAS No.	475250-52-3
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	4-Methoxybenzylboronic Acid Pinacol Ester; (4-Methoxybenzyl)boronic Acid Pinacol Ester; 4-Methoxybenzylboronic Acid, Pinacol Ester; 2-(4-Methoxybenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methoxybenzyl-Bpin; 4-Methoxybenzyl MIDA Boronate (related precursor); p-Methoxybenzylboronic Acid Pinacol Ester; B-(4-Methoxybenzyl)boronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 4-Methoxybenzylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the original container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.