Description

2-(4-Chlorobenzyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 475250-49-8 is a high-purity boronic ester derivative, a crucial organoboron building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to synthesize novel aromatic and heteroaromatic compounds.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing biaryl and substituted aromatic scaffolds in active pharmaceutical ingredient (API) development.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific chlorobenzyl motifs.
• Material Science & OLED Development: Serves as a precursor for creating organic electronic materials, including charge-transport layers and light-emitting compounds.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Polymer Chemistry: Utilized to introduce functional aromatic groups into polymer backbones for specialty polymers.
• Chemical Biology & Probe Development: Acts as a handle for bioconjugation and the synthesis of molecular probes for imaging and diagnostics.

Basic Information

Product Name	2-(4-Chlorobenzyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	475250-49-8
Molecular Formula	C13H18BClO2
Molecular Weight	252.54 g/mol
Synonyms	4-Chlorobenzylboronic Acid Pinacol Ester; (4-Chlorobenzyl)boronic Acid Pinacol Ester; 1-[(4-Chlorophenyl)methyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(4-Chlorobenzyl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; 4-ChlorobenzylBPin; Pinacol (4-Chlorobenzyl)boronate; (4-Chlorobenzyl)BPin
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorobenzyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.