Description

5H-Inden-5-One,1,2,3,3A,4,7A-Hexahydro-1-Methyl-,(1R,3Ar,7Ar)-Rel-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex organic molecules, offering a precise chiral scaffold for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for creating novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to introduce specific stereocenters.
• Medicinal Chemistry Research: Provides a rigid, fused-ring structure for structure-activity relationship (SAR) studies and molecular optimization.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for new chemical entities (NCEs).
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in API manufacturing.
• Academic Research: Used in university and institutional labs for studying novel organic reactions and synthetic methodologies.

Basic Information

Product Name	5H-Inden-5-One,1,2,3,3A,4,7A-Hexahydro-1-Methyl-,(1R,3Ar,7Ar)-Rel-(9Ci)
CAS No.	475051-24-2
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(1R,3aR,7aR)-1-Methyl-1,2,3,3a,4,7a-hexahydro-5H-inden-5-one; rel-(1R,3aR,7aR)-1-Methyloctahydro-5H-inden-5-one; 1-Methyl-1,2,3,3a,4,7a-hexahydro-5H-inden-5-one (relative configuration); 5H-Inden-5-one, 1,2,3,3a,4,7a-hexahydro-1-methyl-, (1R,3aR,7aR)-rel-; Advanced Chiral Indanone Derivative
EINECS	Contact for details

Quality Control

Our 5H-Inden-5-One,1,2,3,3A,4,7A-Hexahydro-1-Methyl-,(1R,3Ar,7Ar)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.