Description

Carbamic Acid, (2,2,2-Trifluoro-1-Methylethyl)-, Ethyl Ester (9Ci) is a specialized fluorinated carbamate ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where the trifluoromethyl group is prized for its ability to modulate biological activity, metabolic stability, and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a trifluoromethyl-substituted moiety to enhance potency and pharmacokinetic profiles.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental stability.
• Organic Synthesis Reagent: Acts as a protected amine equivalent or a versatile electrophile in multi-step synthetic routes for complex organic molecules.
• Material Science Research: Employed in the development of novel fluorinated polymers and specialty materials with unique surface properties and chemical resistance.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and labeled compounds for biochemical and pharmacological research.

Basic Information

Product Name	Carbamic Acid, (2,2,2-Trifluoro-1-Methylethyl)-, Ethyl Ester (9Ci)
CAS No.	474510-48-0
Molecular Formula	C7H10F3NO2
Molecular Weight	197.16 g/mol
Synonyms	Ethyl N-(2,2,2-trifluoro-1-methylethyl)carbamate; 1,1,1-Trifluoro-2-propyl carbamic acid ethyl ester; (2,2,2-Trifluoro-1-methylethyl)carbamic acid ethyl ester; 2,2,2-Trifluoro-1-methylethyl carbamate ethyl ester; Ethyl (2,2,2-trifluoro-1-methylethyl)carbamate; N-(2,2,2-Trifluoro-1-methylethyl)carbamic Acid Ethyl Ester; 9CI Index Name
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, (2,2,2-Trifluoro-1-Methylethyl)-, Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.