Description

1-Iodo-3-Methoxymethoxy-Benzene is a versatile aromatic building block featuring both an iodine substituent and a protected hydroxyl group. This unique bifunctional structure makes it a valuable intermediate in advanced organic synthesis, particularly for cross-coupling reactions and the construction of complex molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop new active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura, Stille, or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides by introducing the aryl iodide moiety into target structures.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and polymers where the methoxymethoxy group offers orthogonal reactivity.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules due to the reactivity of the iodine atom in radiolabeling or bioconjugation strategies.
• Academic & R&D: A fundamental reagent for methodological development in organic chemistry laboratories and for exploring new synthetic pathways.

Basic Information

Product Name	1-Iodo-3-Methoxymethoxy-Benzene
CAS No.	474009-16-0
Molecular Formula	C8H9IO2
Molecular Weight	264.06 g/mol
Synonyms	3-(Methoxymethoxy)iodobenzene; 1-Iodo-3-(methoxymethoxy)benzene; m-(Methoxymethoxy)iodobenzene; 3-Iodophenyl methoxymethyl ether; Benzene, 1-iodo-3-(methoxymethoxy)-; Iodobenzene, 3-(methoxymethoxy)-
EINECS	Contact for details

Quality Control

Our 1-Iodo-3-Methoxymethoxy-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, minimize exposure to light during handling and storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.