Description

Ethyl 4-(4-Chloro-3-Fluorophenyl)-4-Oxobutyrate is a high-purity, versatile organic intermediate characterized by its specific halogenated aromatic ketone ester structure. This compound is critical for the synthesis of complex molecules, offering a key building block for introducing functionalized aryl ketone motifs. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors. Its precise structure enables the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the bioactivity of the halogenated phenyl group.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or optical properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex organic frameworks via reactions at the ketone and ester functional groups.
• Liquid Crystal & OLED Material Development: Investigated as a component in the synthesis of organic electronic materials due to its aromatic and polar characteristics.

Basic Information

Product Name	Ethyl 4-(4-Chloro-3-Fluorophenyl)-4-Oxobutyrate
CAS No.	473693-78-6
Molecular Formula	C12H12ClFO3
Molecular Weight	258.67 g/mol
Synonyms	Ethyl 4-(4-Chloro-3-fluorophenyl)-4-oxobutanoate; 4-(4-Chloro-3-fluorophenyl)-4-oxobutyric Acid Ethyl Ester; 4-Oxo-4-(4-chloro-3-fluorophenyl)butyric Acid Ethyl Ester; Butanoic acid, 4-(4-chloro-3-fluorophenyl)-4-oxo-, ethyl ester; Ethyl 4-(4-Chloro-3-fluorobenzoyl)acetate (tautomeric form); 473693-78-6; 4-(4-Chloro-3-fluorophenyl)-4-oxobutanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 4-(4-Chloro-3-Fluorophenyl)-4-Oxobutyrate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured and tested in facilities that follow cGMP principles where applicable. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.