Description

5-Bromo-2,4-Difluorobenzaldehyde is a versatile and high-purity fluorinated aromatic aldehyde building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique halogen and fluorine substitution pattern enables precise structural modifications. It is primarily sought after by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the bioactivity imparted by the bromo and difluoro substituents.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic compounds for electronic display and lighting applications.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine atom.
• Organic Synthesis Building Block: The aldehyde group allows for further functionalization via condensation, reduction, or oxidation reactions to create diverse chemical libraries.
• Chemical Research & Development: Essential for academic and industrial R&D focused on fluoroorganic chemistry and medicinal chemistry.

Basic Information

Product Name	5-Bromo-2,4-Difluorobenzaldehyde
CAS No.	473416-91-0
Molecular Formula	C7H3BrF2O
Molecular Weight	221.00 g/mol
Synonyms	2,4-Difluoro-5-bromobenzaldehyde; 5-Bromo-2,4-difluorobenzaldehyde; Benzaldehyde, 5-bromo-2,4-difluoro-; 5-Br-2,4-F2C6H2CHO
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,4-Difluorobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.