Description

(2-Methyl-2'-Trifluoromethyl-[1,1'-Biphenyl]-4-Yl)-Carboxylic Acid is a high-purity biphenyl carboxylic acid derivative distinguished by its trifluoromethyl and methyl substituents, offering unique steric and electronic properties. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used as a precursor in developing new-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a backbone for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Material Science Precursor: Employed in the research of organic electronic materials, such as semiconductors and liquid crystals, due to its rigid biphenyl core and fluorine content.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to biotechnology and specialty chemical sectors.

Basic Information

Item	Details
Product Name	(2-Methyl-2'-Trifluoromethyl-[1,1'-Biphenyl]-4-Yl)-Carboxylic Acid
CAS No.	473264-01-6
Molecular Formula	C15H11F3O2
Molecular Weight	280.24 g/mol
Synonyms	2'-Methyl-2-(trifluoromethyl)[1,1'-biphenyl]-4-carboxylic acid; 4'-(Carboxy)-2-methyl-2'-(trifluoromethyl)biphenyl; [1,1'-Biphenyl]-4-carboxylic acid, 2-methyl-2'-(trifluoromethyl)-; Biphenyl-4-carboxylic acid, 2-methyl-2'-trifluoromethyl- derivative
EINECS	Contact for details

Quality Control

Every batch of our (2-Methyl-2'-Trifluoromethyl-[1,1'-Biphenyl]-4-Yl)-Carboxylic Acid is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS. Our quality protocols are designed to meet the stringent requirements of cGMP for pharmaceutical intermediates and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.