Description

2H-Thiopyran,4-Fluorotetrahydro-,1,1-Dioxide(9Ci) is a specialized fluorinated sulfone derivative, serving as a high-value building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a sulfone group, makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides, where the fluorine atom can improve metabolic stability and bioavailability.
• Material Science Research: Acts as a precursor for functionalized polymers or liquid crystals that require specific electronic properties.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes for studying enzyme mechanisms and biological pathways.
• Catalyst Ligand Development: The sulfone moiety can be utilized to develop novel ligands for asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D programs.

Basic Information

Item	Details
Product Name	2H-Thiopyran,4-Fluorotetrahydro-,1,1-Dioxide(9Ci)
CAS No.	473254-32-9
Molecular Formula	C5H7FO2S
Molecular Weight	150.17 g/mol
Synonyms	4-Fluorotetrahydro-2H-thiopyran 1,1-Dioxide; Tetrahydro-4-fluoro-2H-thiopyran 1,1-dioxide; 4-Fluorotetrahydro-2H-thiopyran-1,1-dione; 4-Fluoro-1λ⁶-thiane-1,1-dione; 4-Fluorothiane-1,1-dioxide; 4-Fluorotetrahydrothiopyran-1,1-dioxide; 4-Fluoro-1-thioniacyclohexane 1,1-dioxide
EINECS	Contact for details

Quality Control

Every batch of 2H-Thiopyran,4-Fluorotetrahydro-,1,1-Dioxide(9Ci) is produced under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, NMR, and MS, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions; ensure it is stored separately from such materials to prevent decomposition. Keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.