Description

4'-Bromo-4-Ethoxy-2,3-Difluoro-1,1'-Biphenyl is a high-purity, multi-substituted biphenyl derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, functional materials, and liquid crystal compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or possessing complex polycyclic structures.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging the difluoro and bromo substituents for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a core structural unit in the design of advanced electronic materials for displays and organic light-emitting diodes (OLEDs) due to its rigid biphenyl backbone and substituted pattern.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis, facilitating challenging cross-coupling and functionalization reactions.
• Polymer & Material Science: Acts as a monomer or modifier in the synthesis of high-performance polymers with specific thermal, optical, or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including novel fluorination and arylation reactions.

Basic Information

Product Name	4'-Bromo-4-Ethoxy-2,3-Difluoro-1,1'-Biphenyl
CAS No.	470461-09-7
Molecular Formula	C14H11BrF2O
Molecular Weight	313.14 g/mol
Synonyms	4'-Bromo-4-ethoxy-2,3-difluorobiphenyl; 2,3-Difluoro-4-ethoxy-4'-bromobiphenyl; 1,1'-Biphenyl, 4'-bromo-4-ethoxy-2,3-difluoro-; 4-Ethoxy-2,3-difluoro-4'-bromobiphenyl; [1,1'-Biphenyl]-4-carbonitrile, 4'-bromo-2,3-difluoro-4-ethoxy- (related nitrile derivative); BRN 8515105
EINECS	Contact for details

Quality Control

Our 4'-Bromo-4-Ethoxy-2,3-Difluoro-1,1'-Biphenyl is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be sensitive to strong alkali and fluoride ions; avoid contact with such materials. Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.