Description

4-Amino-3-Methyl-5-Nitro-Benzonitrile is a high-purity, multi-functional aromatic nitrile derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where its unique substitution pattern enables the construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules with heterocyclic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its nitro and amino functional groups.
• Dye and Pigment Manufacturing: Serves as a building block for azo dyes and other complex colorants due to its aromatic amine structure.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic chemistry and medicinal chemistry.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for C-N bond formation.

Basic Information

Product Name	4-Amino-3-Methyl-5-Nitro-Benzonitrile
CAS No.	468741-02-8
Molecular Formula	C8H7N3O2
Molecular Weight	177.16 g/mol
Synonyms	5-Nitro-3-methyl-4-aminobenzonitrile; 4-Amino-3-methyl-5-nitrobenzonitrile; 3-Methyl-5-nitro-4-aminobenzonitrile; Benzonitrile, 4-amino-3-methyl-5-nitro-; 4-Cyano-2-methyl-6-nitroaniline; 2-Methyl-6-nitro-4-cyanoaniline; 4-Amino-3-methyl-5-nitro-benzonitrile
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Methyl-5-Nitro-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.