Description

L-Tarb-No2, 2-(3-Nitrophenyl)-1,3,2-Dioxaborolane-4R,5R-Dicarboxylic Acid is a high-purity, chiral boronic ester derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in facilitating stereoselective carbon-carbon bond formation, particularly in the synthesis of complex pharmaceutical intermediates and fine chemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry, such as protease inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as an organoboron reagent for palladium-catalyzed cross-coupling, enabling the construction of biaryl and other complex molecular architectures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the chiral center and boronate functionality are crucial for biological activity.
• Material Science & OLED Development: Employed as a building block for creating organic semiconductors, liquid crystals, and emissive layers in organic light-emitting diodes (OLEDs).
• Asymmetric Synthesis Catalyst Ligand: The chiral dioxaborolane structure can be utilized to derive ligands for asymmetric catalysis.
• Chemical Biology & Probe Development: Useful for creating molecular probes and sensors that leverage boronic acid-diol interactions for detecting sugars or other biomolecules.

Basic Information

Product Name	L-Tarb-No2, 2-(3-Nitrophenyl)-1,3,2-Dioxaborolane-4R,5R-Dicarboxylic Acid
CAS No.	467443-01-2
Molecular Formula	C11H10BNO8
Molecular Weight	294.01 g/mol
Synonyms	(4R,5R)-2-(3-Nitrophenyl)-1,3,2-dioxaborolane-4,5-dicarboxylic Acid; L-Tartaric Acid Derived (3-Nitrophenyl)boronic Ester; (R,R)-2-(3-Nitrophenyl)-1,3,2-dioxaborolane-4,5-dicarboxylic Acid; 2-(3-Nitrophenyl)-4,5-O-(R,R)-dihydroxysuccinyl-1,3,2-dioxaborolane; 3-Nitrophenylboronic Acid L-Tartaric Acid Ester; Chiral Nitrophenylboronate Ester; L-Tarb-NO2 Reagent.
EINECS	Contact for details

Quality Control

Our L-Tarb-No2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the stringent requirements of research and process chemistry. A detailed Certificate of Analysis (COA) documenting identity, purity (assay), chiral excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.