Description

1-(2,6-Difluorophenyl)-2-Phenyl-1-Ethanone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in its unique difluorophenyl and phenylacetyl structural motifs, which are pivotal for modulating the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, serving as a key intermediate for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, where the fluorine atoms enhance metabolic stability and bioavailability.
• Material Science: Serves as a monomer or building block for specialty polymers and liquid crystals, contributing to thermal stability and optical properties.
• Organic Synthesis: Employed in cross-coupling reactions, Friedel-Crafts acylation, and as a scaffold for constructing complex heterocyclic compounds in academic and industrial R&D.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1-(2,6-Difluorophenyl)-2-Phenyl-1-Ethanone
CAS No.	465514-59-4
Molecular Formula	C14H10F2O
Molecular Weight	232.23 g/mol
Synonyms	2',6'-Difluorochalcone; 2,6-Difluorochalcone; (2,6-Difluorophenyl)phenacyl ketone; 1-(2,6-Difluorophenyl)-2-phenylethanone; 2-Phenyl-1-(2,6-difluorophenyl)ethanone; α-Phenyl-2,6-difluoroacetophenone; DFPE
EINECS	Contact for details

Quality Control

Our 1-(2,6-Difluorophenyl)-2-Phenyl-1-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.